Starvation-Sensitized and Oxygenation-Promoted Tumor Sonodynamic Therapy by a Cascade Enzymatic Approach
نویسندگان
چکیده
منابع مشابه
Sonodynamic Therapy Using Protoporphyrin IX Conjugated to Gold Nanoparticles: An In Vivo Study on a Colon Tumor Model
Objective(s) Sonodynamic therapy is a physical treatment which utilizes ultrasound waves with an appropriate sensitizer such as protoporphyrin IX (PpIX). The activation of sensitizer depends on cavitation, and therefore, high intensity ultrasound is an important necessity. Beside, high intensity ultrasound can induce side effects on the healthy tissues which have surrounded tumor. The particle...
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Studies of sonodynamic therapy (SDT) have mainly focused on its direct cytotoxic effect on tumor cells. Its effects on the tumor microenvironment, especially angiogenesis, remain unknown. In this study, we found that SDT significantly inhibited endothelial cell proliferation, migration, invasion, and tube formation. Furthermore, in a tumor xenograft mouse model, SDT was found to remarkably supp...
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The low-intensity ultrasound that is used in clinical diagnoses, such as abdomen echo inspection, is a non-invasive treatment, and penetrates deeper into the body than light. Recently, sonodynamic therapy (SDT), which uses low-intensity ultrasound together with a sonosensitizer, has been developed for cancer therapy in applying such properties of ultrasound. So far, most sonosensitizers that ha...
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بنا براستدلال زبانشناسان شناختی ، اندیشه آدمی تا حدّ زیادی استعاری است: ما اندیشه ای را، و یا قلمرو مفهومی معیّنی را، بر حسب اندیشه و یا قلمرو مفهومی معیّن دیگری درک ویا تجربه می کنیم. موارد این نوع اندیشیدن ، که استعارات مفهومی خوانده می شوند، در زبان های گوناگون به صورت تعبیرات استعاری واقعیّت می یابند. به گمان بعضی از پزوهشگران زبان دوم، آموزش وفراگیری این گونه تعبیرات باید بخشی لازم از برنامه ه...
15 صفحه اولEffects of Combined Sonodynamic and Photodynamic Therapies on a Colon Carcinoma Tumor Model
Objective(s) Although photodynamic therapy is considered as a noninvasive method, most photosensitizers are susceptible to ultrasound. Therefore, it is expected that the combination of two activation methods might have a synergistic effect. This probable effect has been investigated in this study. Materials and Methods This study was conducted on colon carcinoma ...
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ژورنال
عنوان ژورنال: Research
سال: 2021
ISSN: 2639-5274
DOI: 10.34133/2021/9769867